Detection and characterization of breast masses with ultrasound tomography: clinical results
Proceedings of SPIE(2009)
摘要
We report on a continuing assessment of the in-vivo performance of an operator independent breast imaging device
based on the principles of acoustic tomography. This study highlights the feasibility of mass characterization using
criteria derived from reflection, sound speed and attenuation imaging. The data were collected with a clinical prototype
at the Karmanos Cancer Institute in Detroit MI from patients recruited at our breast center. Tomographic sets of images
were constructed from the data and used to form 3-D image stacks corresponding to the volume of the breast. Masses
were identified independently by either ultrasound or biopsy and their locations determined from conventional
mammography and ultrasound exams. The nature of the mass and its location were used to assess the feasibility of our
prototype to detect and characterize masses in a case-following scenario.
Our techniques generated whole breast reflection images as well as images of the acoustic parameters of sound speed
and attenuation. The combination of these images reveals major breast anatomy, including fat, parenchyma, fibrous
stroma and masses. The three types of images are intrinsically co-registered because the reconstructions are performed
using a common data set acquired by the prototype. Fusion imaging, utilizing thresholding, is shown to visualize mass
characterization and facilitates separation of cancer from benign masses. These initial results indicate that operatorindependent
whole-breast imaging and the detection and a characterization of cancerous breast masses are feasible using
acoustic tomography techniques.
更多查看译文
关键词
ultrasonography,ultrasound,cancer,tomography,reflection
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要