Inhibitory effect of anthocyanin-rich black soybean testa ( Glycine max (L.) Merr.) on the inflammation-induced adipogenesis in a DIO mouse model

So Young Kim, Haeri Wi,Seojin Choi,Tae Joung Ha,Byong Won Lee,Myoungsook Lee

Journal of Functional Foods（2015）

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摘要

•We found there are three major anthocyanins in the ethanol extract from seed coat of black soybean (BB): C3G, D3G, and P3G.•BB significantly decreases food intake and fat accumulation in DIO C57BL/6N mouse model.•We demonstrated the successful lipolysis-promoting effects of BB; the upregulation of HSL, LPL and p-AMPK expression.•Our result confirms the anti-inflammatory effect of BB; the downregulation of TNF-α and IL-6 expression.

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关键词

ACC,ALT,AMPKα,ANOVA,AST,ATGL,BBC,C/EBPα,C/EBPβ,C/EBPγ,C3G,C57BL/6N,CON,D3G,DAG,DIO,ELISA,FAS,FFA,GAPDH,H&E,HF,HPLC,HSL,IL-1,IL-6,IL-10,LPL,LPS/IFN-γ,MAG,MCP-1,MDA,O,p-AMPKα,P3G,PCR,PPARγ,RT-PCR,SDS-PAGE,SREBP-1,TBARS,TC,TG,TNF-α

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