Back Cover: Diversified Structural Basis of a Conserved Molecular Mechanism for Ph‐dependent Dimerization in Spider Silk N‐Terminal Domains (chembiochem 12/2015)
ChemBioChem(2015)
摘要
The back cover picture shows the dimerization of the spider silk N-terminal domain as part of silk fiber formation. On p. 1720 ff., J. Johansson, K. Jaudzems and co-workers show that the dimerization involves a stepwise uptake of three protons by three glutamic acids. This mechanism is conserved among different spider species and silk types despite sequence variations.
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