Prediction Of Cancer Possibility By Pattern Recognition And Statistical Study Of Expression Of Gene Level Of Cancer Cells

Nature Precedings(2011)

引用 0|浏览1
暂无评分
摘要
The activity of the p53 tumor-suppressor protein has a key role in controlling both cancer and aging: under activity encourages the growth of cancer, and over activity can accelerate the aging process. The p53 protein is a tumor suppressor encoded by a gene whose disruption is associated with approximately 50 to 55 percent of human cancers. The p53 protein acts as a checkpoint in the cell cycle, either preventing or initiating programmed cell death (Apoptosis). p53 regulating genes MDM2, PARP, Oncogenicras, and p21 etc play a crucial role in tumor suppression.
更多
查看译文
关键词
apoptosis,p53,p21,MDM2,tumor-suppressor
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要