Homocysteine Induces Reactive Oxygen Species-Dependent Apoptosis Of Arterial Smooth Muscle Cells Coinciding With (Peri)Nuclear Nox4 Translocation

Nynke E. Hahn,Jessica A. Sipkens,Melissa Wassink, Alexander B. Vonk, Coen D. Stehouwer,Jan A. Rauwerda,Victor W. Van Hinsbergh,Christof Meischl,Hans W. Niessen,Paul A. Krijnen

Circulation（2011）

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摘要

Background: Elevated levels of homocysteine form a vascular risk factor. Although a jeopardizing role of homocysteine on endothelial cells has been shown, its effect on smooth muscle cells is contr...

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关键词

Reactive oxygen intermediates, Apoptosis, Smooth muscle

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