Rhamnolipids functionalized AgNPs-induced oxidative stress and modulation of toxicity pathway genes in cultured MCF-7 cells

Colloids and Surfaces B: Biointerfaces, pp. 290-298, 2015.

Cited by: 13|Bibtex|Views1|DOI:https://doi.org/10.1016/j.colsurfb.2015.05.034
Other Links: academic.microsoft.com|www.sciencedirect.com

Abstract:

•Biosurfactant rhamnolipids were extracted from P. aeruginosa culture extract.•Non-toxic concentration (0.005%) of rhamnolipids was used for synthesis of Rh-AgNPs.•Rh-AgNPs exhibited more cytotoxicity to MCF-7 cells than normal PBMN cells.•Rh-AgNPs caused ROS generation, membrane damage and apoptosis in MCF-7 cells.•Oxidative stress pathw...More

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