Tu1855 Increase in Dietary Fiber Dampens Intestinal Inflammation and Restores Mucosal Integrity in Chronically Stressed Mice: Mediation Via Activation of CD103+ Dendritic Cells and Fox P3 Regulatory T-Cells

with LPS in vitro.Overexpression of TGR5 resulted in increased PCNA, CCK8, EdU incorporation and the proportion of cells in S phase, whereas, knockdown of TGR5 caused an opposite effect.Conclusions: Bile acids could promote intestinal epithelial cell proliferation and reduce the mucosal injury by upregulating the expression of TGR5 in obstructive jaundice.