Su1076 Measurement of Esophago-Gastric Junction Cross-Sectional Area and Distensibility by Endoflip® (Endolumenal Functional Lumen Imaging Probe) for the Diagnosis of Patients With Gastro-Esophageal Reflux Disease (GERD)

acidic reflux (1 patient was negative for acid refluxes and weakly acidic refluxes separately, but was positive considering both refluxes as a whole).Twenty-eight (41%) patients had no association between reflux and symptoms.Identifying patients with symptomatic weakly acidic reflux reduces the number of patients with unexplained chest pain from 91 (46%) to 64 (32%) and from 51 (75%) to 28 (41%) among patients off-PPI and on-PPI, respectively (p<0.01).Conclusion: Monitoring for weakly acidic reflux in NCCP patients increases our ability to identify patients in whom symptoms are associated with reflux, mainly in patients on-PPI therapy.Our data support the use of ambulatory impedance-pH monitoring in a diagnostic algorithm for patients with unexplained chest pain.The impact of this improved diagnostic value on NCCP management remains to be investigated by outcome studies.