Ascites predicts treatment benefit of bevacizumab in front-line therapy of advanced epithelial ovarian, fallopian tube and peritoneal cancers: An NRG Oncology/GOG study

James Stuart Ferriss,J Java,Michael A Bookman,Gini F Fleming,Bradley J Monk,Joan L Walker,Howard D Homesley,Jeffrey M Fowler,Benjamin E Greer,Matthew Boente,Robert A Burger

Gynecologic Oncology（2015）

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摘要

•We analyzed data from GOG 0218 to determine if ascites predicts response to bevacizumab.•Ascites was shown to be a negative prognostic factor in epithelial ovarian cancers.•Ascites is a significant clinical factor that may predict response to bevacizumab.

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关键词

Bevacizumab,Advanced epithelial ovarian cancer,Front-line therapy,NRG Oncology,GOG

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