Differential regulation of caspase-2 in MPP + -induced apoptosis in primary cortical neurons

Experimental Cell Research, pp. 60-66, 2015.

Cited by: 0|Bibtex|Views7|DOI:https://doi.org/10.1016/j.yexcr.2015.01.011
Other Links: academic.microsoft.com|www.sciencedirect.com

Abstract:

Parkinson׳s disease (PD), among the most common neurodegenerative diseases worldwide for which there is no cure, is characterized as progressive dopaminergic neuron loss in the substantia nigra through an unknown mechanism. Administering 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) causes neuronal cell death and Parkinsonism in ...More

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