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Wnt1 Inducible Signaling Pathway Protein 1 (WISP1) Is a Novel Adipokine Linked to Inflammation and Insulin Resistance in Visceral Fat

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES(2014)

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Abstract
Introduction: WISP1 is a member of the CCN family of extracellular matrix proteins and target gene of Wnt signaling pathway. Here we show that WISP1 is released from adipocytes and WISP1 expression correlate with weight loss and signs of insulin resistance.
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Key words
wisp1,novel adipokine,insulin resistance,pathway protein,inflammation
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