Gold(Iii) Tetraarylporphyrin Phosphonate Derivatives As Potential Anticancer Agents

5-[4-(Dialkyoxyphosphorylamino)]phenyl-10,15,20- triphenylporphyrinato gold(III)chlorides have been synthesised and evaluated for their in vitro cytotoxic activity against SMMC-7721 human hepatic and sarcoma 180 mouse cancer cell line panels. 5-[4-(Diisopropoxyphosphorylamino)]phenyl-10,15,20- triphenylporphyrinato gold(III)chloride exhibited significant growth inhibitory properties against sarcoma 180 mouse cancer cells (IC50 value = 2.60 μM) and 5-[4-(dipropoxyphosphorylamino)]phenyl-10,15,20-triphenylporphyrinato gold(III)chloride showed significant growth inhibitory properties against SMMC-7721 human hepatic cancer cells (IC50 value = 5.10 μM).