1-Phenyl-2-pyrrolidinyl-cyclopentylamine via Thermal Rearrangement

SYNTHETIC COMMUNICATIONS(2011)

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摘要
[image omitted] Thermal rearrangement of aminoimine, 1, followed by hydrogenation produced 1-phenyl-2-pyrrolidinyl cyclopentylamine 3. The structure and stereochemistry of this novel amine 4 was identified by x-ray crystallography of the 2-chloro-6-iodo-nicotinamide derivative as a hydrogen maleate salt.
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关键词
1-Phenyl-2-pyrrolidinyl-cyclopentylamine,thermal rearrangement,X-ray structure
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