343 Persistence of Non Dysplastic Barrett's Esophagus is Not Protective Against Progression to Adenocarcinoma: Results from a Prospective Be-EAC Registry

Endoscopic surveillance for patients with nondysplastic Barrett's esophagus (NDBE) is recommended due to risk of progression to esophageal adenocarcinoma (EAC). Recent studies have shown that the risk of progression to EAC in NDBE subjects is lower than previously estimated. Evidence on the risk of progression to EAC over time and persistence of NBDE on repeated biopsies predicting lower risk of progression is conflicting. This study aimed to investigate if persistence of NBDE in consecutive biopsies reduced the risk of progression to EAC, which may justify prolonging surveillance intervals in some subjects.