Glutamate Transporters/Na+, K+-ATPase Involving in the Neuroprotective Effect as a Potential Regulatory Target of Glutamate Uptake

Molecular Neurobiology, Volume 53, Issue 2, 2015, Pages 1124-1131.

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Keywords:
Na+ K+-ATPase Glutamate transporter Coupling/uncoupling Glutamate uptakeMore(1+)

Abstract:

The glutamate (Glu) transporters GLAST and GLT-1, as the two most important transporters in brain tissue, transport Glu from the extracellular space into the cell protecting against Glu toxicity. Furthermore, GLAST and GLT-1 are sodium-dependent Glu transporters (GluTs) that rely on sodium and potassium gradients generated principally by ...More

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