Experimental Infection And Response To Rechallenge Of Alpacas With Middle East Respiratory Syndrome Coronavirus

Gary Crameri,Peter A. Durr, Reuben Klein,Adam Foord,Meng Yu,Sarah Riddell, Jessica Haining,Dayna Johnson,Maged G. Hemida,Jennifer Barr,Malik Peiris,Deborah Middleton,Lin-Fa Wang

EMERGING INFECTIOUS DISEASES（2016）

引用 47|浏览2

暂无评分

摘要

We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. The alpacas shed virus at challenge but were refractory to further shedding at rechallenge on day 21. The trial indicates that alpacas may be suitable models for infection and shedding dynamics of this virus.

查看译文

关键词

MERS-CoV,Middle East respiratory syndrome,SARS,alpaca,camel,coronavirus,experimental animal model,infection,rechallenge,severe acute respiratory syndrome,shedding,vaccine,viruses,zoonoses

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要