Glycoholics Anonymous: Cancer Sobers Up with mTORC1.
Cancer Cell（2016）
摘要
In this issue of Cancer Cell, Pusapati et al. (2016) reveal that mTORC1 orchestrates the metabolic reprogramming of cancer cells in response to glycolytic inhibitors, bypassing glycolysis by increasing glutamine uptake and pentose phosphate flux to generate energy and biomass.
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