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Effects of Gene Dose, Chromatin, and Network Topology on Expression in Drosophila melanogaster.

PLOS GENETICS, no. 9 (2016): e1006295-e1006295

Cited by: 22|Views22
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Abstract

Deletions, commonly referred to as deficiencies by Drosophila geneticists, are valuable tools for mapping genes and for genetic pathway discovery via dose-dependent suppressor and enhancer screens. More recently, it has become clear that deviations from normal gene dosage are associated with multiple disorders in a range of species includ...More

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