Purinergic receptors in the carotid body as a new drug target for controlling hypertension

Wioletta Pijacka,Davi J A Moraes,Laura E K Ratcliffe,Angus K Nightingale,Emma C Hart,Melina P da Silva,Benedito H Machado,Fiona D McBryde,Ana P Abdala,Anthony P Ford,Julian F R Paton

NATURE MEDICINE（2016）

引用 146|浏览14

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摘要

small-molecule antagonist of the P2X3 receptor reduces blood pressure in hypertensive rats via its action on the carotid body, pointing to a new drug target for treating hypertension.

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关键词

Translational research,Hypertension,Preclinical research

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