Identification of context-dependent expression quantitative trait loci in whole blood

NATURE GENETICS(2016)

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Abstract
Bastiaan Heijmans, Peter ’t Hoen, Lude Franke and colleagues describe a strategy to identify context-dependent expression quantitative trait loci (eQTLs). They apply their method to peripheral blood RNA–seq data from 2,116 unrelated individuals and discover 23,060 significant cis -regulated genes, of which 12% showed context-dependent eQTL effects.
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Key words
Genome informatics,Population genetics,Gene expression
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