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Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer

Di Zhao,Xin Lu,Guocan Wang,Zhengdao Lan,Wenting Liao,Jun Li,Xin Liang,Jasper Robin Chen, Sagar Shah,Xiaoying Shang,Ming Tang,Pingna Deng,Prasenjit Dey,Deepavali Chakravarti,Peiwen Chen,Denise J. Spring,Nora M. Navone,Patricia Troncoso,Jianhua Zhang,Y. Alan Wang,Ronald A. DePinho

NATURE（2017）

引用 185|浏览9
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摘要
The gene CHD1 is synthetic essential in PTEN-deficient prostate and breast cancers.
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关键词
Cancer genomics,Prostate cancer
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