Absorption, Distribution, Metabolism, and Excretion (ADME) of 14 C-sonidegib (LDE225) in Healthy Volunteers

Markus Zollinger,Frédéric Lozac’h,Eunju Hurh,Corinne Emotte,Hounayda Bauly,Piet Swart

Cancer chemotherapy and pharmacology（2014）

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摘要

The absorption, distribution, metabolism, and excretion of the hedgehog pathway inhibitor sonidegib (LDE225) were determined in healthy male subjects.

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关键词

Absorption,Distribution,Metabolism,Excretion,Hedgehog,Sonidegib (LDE225)

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