Phase-Based Registration of Cardiac Tagged MR Images by Incorporating Anatomical Constraints.

This paper presents a novel method that combines respective benefits of the tracking-based methods and the Gabor-based non-tracking approaches for improving the motion/strain quantification from tagged MR images. The "tag number constant" concept used in Gabor-based non-tracking methods is integrated into a recent phase-based registration framework. We evaluated our method on both synthetic and real data: (1) on a synthetic data of a normal heart, we found that the constraint improved both longitudinal and circumferential strains accuracies; (2) on 15 healthy volunteers, the proposed method achieved better tracking accuracy compared to three state-of-the-art methods; (3) on one patient dataset, we show that our method is able to distinguish the infarcted segments from the normal ones.