Host response: Neurons loosen the gRIP of death

NATURE MICROBIOLOGY（2017）

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摘要

RIPK3 is a well-known mediator of the necroptosis cell death pathway, which is an important antiviral defence mechanism. In an unexpected twist, RIPK3 has now been shown to also drive neuroprotective inflammation in the central nervous system during West Nile virus infection in a cell-death-independent manner.

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关键词

Cell death and immune response,Chemokines,West nile virus,Life Sciences,general,Microbiology,Medical Microbiology,Parasitology,Infectious Diseases,Virology

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