Drug–target interaction prediction by integrating multiview network data

Computational Biology and Chemistry(2017)

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摘要
Drug–target interaction (DTI) prediction is a challenging step in further drug repositioning, drug discovery and drug design. The advent of high-throughput technologies brings convenience to the development of DTI prediction methods. With the generation of a high number of data sets, many mathematical models and computational algorithms have been developed to identify the potential drug–target pairs. However, most existing methods are proposed based on the single view data. By integrating the drug and target data from different views, we aim to get more stable and accurate prediction results.
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关键词
Drug–target interaction prediction,Multiview clustering,Data integration
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