Molecular Characteristics Of Mcr-1-Carrying Plasmids And New Mcr-1 Variant Recovered From Polyclonal Clinical Escherichia Coli From Argentina And Canada
PLOS ONE(2017)
摘要
We have characterized nine mcr-1-harboring plasmids from clinical Escherichia coli isolates previously described in Argentina and Canada. Three of these plasmids carried a mcr-1-variant called here mcr-1.5. All these E. coli isolates were not clonally related and were recovered in different years and locations. However, their mcr-1-harboring plasmids showed high identity among them and to others characterized in other countries, which strongly suggests that this plasmid-type is playing an important role in spreading this mechanism of resistance to polymyxins.
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关键词
polyclonal clinical escherichia coli,escherichia coli,plasmids
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