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Neurokinin 3 Receptor Antagonism Decreases Gonadotropin and Testosterone Secretion in Healthy Men

Karolina Skorupskaite,Jyothis T. George,Johannes D. Veldhuis,Robert P. Millar,Richard A. Anderson

Clinical endocrinology（2017）

Cited 18|Views42
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Abstract
Patients with mutations of neurokinin B (NKB) and its receptor show hypogonadotrophic hypogonadism, but there is little evidence for the importance of this pathway in reproductive function in normal men, or its functional hierarchy with kisspeptin.
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Key words
GnRH pulsatility,gonadotrophins,kisspeptin,neurokinin B,testosterone
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