Raw starch microparticles have immunostimulant activity in mice vaccinated with BCG and challenged with Mycobacterium tuberculosis.

Silvia Moreno-Mendieta,Jorge Barrios-Payán,Dulce Mata-Espinosa,Sergio Sánchez,Rogelio Hernández-Pando,Romina Rodríguez-Sanoja

Vaccine（2017）

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摘要

•A mucosal vaccine adjuvant based on starch is proposed.•The immunostimulant properties of raw starch microparticles in vivo was demonstrated.•Their administration asa nasal booster improved the protection achieved with BCG vaccine.

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关键词

Starch microparticles,Vaccine adjuvant,Mucosal immunization,Innate immunity,Tuberculosis

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