Automated segmental-IMT measurement in thin/thick plaque with bulb presence in carotid ultrasound from multiple scanners: Stroke risk assessment.

•Automated detection of the carotid bulb edge, which is considered a reference marker for measurements of the cIMT.•Automated segment-based cIMT measurement system which estimates the cIMT for different segments of the carotid artery proximal to the bulb edge.•Segmental-IMT (sIMT) allows us to measure IMT in 10 mm segments (namely: s1, s2 and s3) proximal to the bulb edge.•The proposed fully automated bulb detection system achieved 92.67% precision against ideal bulb edge locations in the bulb transition zone and holds a significant promise for risk stratification tool for carotid disease.