Kras G12D upregulates Notch signaling to induce gallbladder tumorigenesis in mice.

Oncoscience（2017）

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摘要

Kras induces gallbladder adenoma and Notch plays a key role in Kras-initiated gallbladder tumorigenesis.

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关键词

Kras mutation,Notch signaling,adenoma,gallbladder tumorigenesis,mouse model

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