The role of the p38-activated protein kinase signaling pathway-mediated autophagy in cadmium-exposed monogonont rotifer Brachious koreanus.

Hye-Min Kang,Chang-Bum Jeong,Min-Sub Kim,Jin-Sol Lee,Jiaying Zhou,Young Hwan Lee,Duck-Hyun Kim,Eunyoung Moon,Hee-Seok Kweon,Su-Jae Lee,Jae-Seong Lee

Aquatic Toxicology（2018）

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摘要

•Conserved autophagy in the rotifer B. koreanus was verified.•p38 MAPK-mediated autophagy regulation in B. koreanus in response to cadmium-induced oxidative stress.•Involvement of ERK and JNK in basal autophagy regulation.

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关键词

Autophagy,LC3 I/II,Mitogen-activated protein kinases,p38 MAPK,Rotifer

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