Inhibition of Porcine Endogenous Retrovirus by Multi-Targeting Micro RNA Against Long Terminal Region.

Transplantation Proceedings(2017)

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摘要
•This study suggested that the LTR might be an alternative target for gene silencing of PERV, and that multi-targeting miRNA had better inhibitory effect than single- targeting miRNA.•In an in vitro model, the presence of miRNA was able to reduce PERV infectivity in a human cell line.
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关键词
porcine endogenous retrovirus,rna,multi-targeting
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