Impact Of Anti-Infective Periodontal Therapy On Parameters Of Vascular Health

AimThis study assessed the impact of anti-infective periodontal therapy on the status of vascular health.Materials and MethodsPeriodontal and vascular health of 55 patients with severe untreated chronic periodontitis was evaluated before and 12months after anti-infective periodontal therapy. Observed parameters were bleeding on probing (BoP), pocket probing depth (PPD), periodontal inflamed surface area index (PISA), pulse wave velocity (PWV), augmentation index (AIx), central pulse pressure (PPao) and peripheral systolic pressure (RRsys).ResultsPISA (baseline-12months) correlated with PWV ( 0.21; p<.03), AIx ( 0.29; p<.002) and PPao ( 0.23; p<.02). BoP% (baseline-12months) correlated with PWV ( 0.18; p<.05) and AIx ( 0.25; p<.01), while mean PPD (baseline-12months) correlated with PWV ( 0.24; p<.01) and AIx ( 0.21; p<.03). Grouping patients evenly into three groups based on tertiles of BoP resolution after 12months revealed a significant decrease in the observed PWV median value by -0.6m/s (p<.04) in the best response tertile (BoP 88%). In the worst response tertile (BoP66%), by contrast, significant increase in PPao (+10.5mmHg; p<.02) and AIx (+5.5; p<.02) was observed.ConclusionEfficacious resolution of periodontal inflammation may beneficially impact on vascular health.