Type F Infant Botulism: Investigation of Recent Clusters and Overview of This Exceedingly Rare Disease.

Alison Laufer Halpin,Jessica M Khouri,Jessica R Payne, Jolene H Nakao,Alicia Cronquist,Nicholas Kalas,Marika Mohr,Matthew Osborne, Sharon O'Dell,Carolina Luquez,Karl C Klontz,Jeremy Sobel,Agam K Rao

CLINICAL INFECTIOUS DISEASES（2018）

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摘要

From 1976 to 2016, neurotoxigenic Clostridium baratii type F caused 18 (< 0.5%) reported US infant botulism cases. Six cases occurred during 2012-2013; no common source was identified. Type F infant botulism mostly occurs in very young infants and typically presents more rapidly and severely than illness caused by types A and B botulinum neurotoxin.

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关键词

infant botulism,Clostridium baratii,botulinum toxin,clinical spectrum,molecular epidemiology

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