Specific labeling of mitochondria of Chlamydomonas with cationic helicene fluorophores
Organic & Biomolecular Chemistry(2018)
摘要
Twelve cationic helicenes and one triangulene were tested for the specific labeling of mitochondria from algal cells. Octyl ester derivative 5 readily penetrates algal cells and gives rise to clear fluorescence patterns when it is used at concentrations in the mu M range. Under these conditions, cell structures are well preserved and cell survival is not compromised. Cationic helicene compounds such as 5 provide new useful tools for examining the mitochondrial network and its dynamics including fission and fusion events.
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关键词
mitochondria,cationic helicene fluorophores,specific labeling
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