Differential expression of the immediate early genes c-Fos, Arc, Egr-1, and Npas4 during long-term memory formation in the context preexposure facilitation effect (CPFE)

Nicholas A. Heroux,Brittany F. Osborne,Lauren A. Miller,Malak Kawan,Katelyn N. Buban,Jeffrey B. Rosen,Mark E. Stanton

Neurobiology of Learning and Memory（2018）

引用 42|浏览25

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摘要

•The CPFE separately assesses memory of context vs. context fear.•Context learning induces expression of IEGs (c-Fos, Arc, Egr-1, and Npas4) in mPFC, dHPC and BLA.•Fear learning drives expression of these same IEGs in mPFC, plus c-Fos in dHPC and Egr-1 in BLA.

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关键词

CPFE,Contextual fear conditioning,Medial prefrontal cortex,Context learning,Immediate early genes

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