CREB, cellular excitability, and cognition: Implications for aging
Behavioural Brain Research(2017)
摘要
•Biophysical and cognitive deficits are linked in aging.•CREB modulates biophysics and cognition in young adult animals.•CREB dysfunction may underlie biophysical and cognitive changes in aging.•CREB may be a therapeutic target for age-related cognitive deficits.
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关键词
AHP,BDNF,caCREB,CRE,CREB,EGR-1,LTP
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