Modelling the Release of Moxifloxacin from Plasma Grafted Intraocular Lenses with Rotational Symmetric Numerical Framework.

IWBBIO(2018)

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摘要
A rotational symmetric finite element model is constructed to simulate the release of moxifloxacin from different types of plasma-grafted intraocular lenses, utilizing general discontinuous boundary conditions to describe the interface between lens and outside medium. Such boundary conditions allow for the modelling of partitioning and interfacial mass transfer resistance. Due to its rotational symmetry, the shape of the optical part of the intraocular lens is fully taken into account.
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关键词
Plasma-grafting, Discontinuities, Finite element, Mass transfer, Partitioning, Targeted drug delivery, Ocular drug delivery
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