PepCVAE: Semi-Supervised Targeted Design of Antimicrobial Peptide Sequences.

Kahini Wadhawan
Kahini Wadhawan
Oscar Chang
Oscar Chang
Tom Sercu
Tom Sercu
Matthew Riemer
Matthew Riemer

arXiv: Quantitative Methods, Volume abs/1810.07743, 2018.

被引用5|浏览72
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摘要

Given the emerging global threat of antimicrobial resistance, new methods for next-generation antimicrobial design are urgently needed. We report a peptide generation framework PepCVAE, based on a semi-supervised variational autoencoder (VAE) model, for designing novel antimicrobial peptide (AMP) sequences. Our model learns a rich latent ...更多

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