Characterization of an Orthotopic Colorectal Cancer Mouse Model and Its Feasibility for Accurate Quantification in Positron Emission Tomography

Sara Rapic,Christel Vangestel,Jeroen Verhaeghe,Tim Van den Wyngaert,Rukun Hinz,Marleen Verhoye,Patrick Pauwels,Steven Staelens,Sigrid Stroobants

Molecular imaging and biology（2017）

引用 6|浏览6

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摘要

Quantification in positron emission tomography (PET) imaging of an orthotopic mouse model of colorectal cancer (CRC) is challenging due to difficult tumor delineation. We aimed to establish a reproducible delineation approach, evaluate its feasibility for reliable PET quantification and compare its added translational value with its subcutaneous counterpart.

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关键词

Positron emission tomography,Magnetic resonance imaging,Contrast enhanced computed tomography,Tumor delineation,Orthotopic mouse model,Colorectal cancer

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