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Hydrodynamics of a free-flowing leukocyte toward the endothelial wall.

Microvascular Research(2017)

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摘要
Leukocyte recruitment is an essential stage of the inflammatory response and although the molecular mechanisms of this process are relatively well known, the influence of the hydrodynamic effects that govern the inflammatory response are still under study. In this paper we made use of the images and experimental parameters obtained by intravital microscopy in an in vivo animal model of inflammation to track the leukocytes trajectories and measure their velocities and diameters.
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关键词
Leukocyte,Inflammatory response,Intravital microscopy,Mathematical model,Coupled deformation-flow,Numerical simulations
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