Mir-422A Inhibits Cell Proliferation in Colorectal Cancer by Targeting AKT1 and MAPK1
Cancer Cell International(2017)
摘要
miRNAs are regarded as molecular biomarkers and therapeutic targets for colorectal cancer (CRC), a series of miRNAs have been proven to involve into CRC carcinogenesis, invasion and metastasis. Aberrant miR-422a expression and its roles have been reported in some cancers. However, the function and underlying mechanism of miR-422a in the progression of CRC remain largely unknown.
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关键词
miR-422a,Proliferation,Prognosis,Colorectal cancer,AKT1,MAPK1
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