Time-courses of plasma IL-6 and HMGB-1 reflect initial severity of clinical presentation but do not predict poor neurologic outcome following subarachnoid hemorrhage.

Heikki Kiiski,Jaakko Långsjö,Jyrki Tenhunen, Marika Ala-Peijari,Heini Huhtala,Mari Hämäläinen,Eeva Moilanen,Juha Öhman,Jukka Peltola

eNeurologicalSci（2017）

引用 14|浏览12

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摘要

•IL-6 reflects the intensity of inflammation after aSAH without association to neurological outcome.•Early inflammatory response might even be beneficial after aSAH.•Lack of correlation between IL-6 and HMGB1 questions the role of macrophages in inflammatory response after aSAH.

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关键词

Aneurysmal subarachnoid hemorrhage,Biomarkers,Neuroinflammation,Inflammatory response,Il-6,HMGB1

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