Bulk production and evaluation of high specific activity 186g Re for cancer therapy using enriched 186 WO 3 targets in a proton beam.

Tara Mastren,Valery Radchenko, Hong T Bach,Ethan R Balkin,Eva R Birnbaum,Mark Brugh,Jonathan W Engle,Matthew D Gott,James Guthrie,Heather M Hennkens,Kevin D John,Alan R Ketring,Marina Kuchuk,Joel R Maassen,Cleo M Naranjo,F Meiring Nortier,Tim E Phelps,Silvia S Jurisson,D Scott Wilbur,Michael E Fassbender

Nuclear Medicine and Biology（2017）

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摘要

We report a preliminary study of the large-scale production and novel anion exchange based chemical recovery of high specific activity Re from enriched WO targets in a high-intensity proton beam with exceptional chemical recovery and radiochemical purity.

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关键词

Theranostic,186gRe,186WO3 target,High specific activity,Radiolabeling,SPECT phantom images

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