Increased expression of the adipocytokine omentin in the epicardial adipose tissue of coronary artery disease patients.

Ken Harada,Rei Shibata,Noriyuki Ouchi,Yoshiyuki Tokuda,Hiroshi Funakubo,Mayu Suzuki,Takashi Kataoka,Tomoyuki Nagao,Satoshi Okumura,Norihiro Shinoda,Bunichi Kato,Shinichi Sakai,Masataka Kato,Nobuyuki Marui,Hideki Ishii,Tetsuya Amano,Tatsuaki Matsubara,Toyoaki Murohara

Atherosclerosis（2016）

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摘要

•Omentin increased in the epicardial fat of coronary artery disease (CAD) patients.•Omentin present in subcutaneous fat was unchanged in CAD patients.•Epicardial fat volume increased in CAD patients, but was not related to omentin.•Plasma omentin were negatively associated with omentin in epicardial fat in CAD patients.•Our findings suggest omentin is involved in pathogenesis of non-obese CAD patients.

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关键词

Omentin,Epicardial adipose tissue,Subcutaneous adipose tissue,Coronary artery disease,Non-obese

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