Direct-acting antiviral therapy enhances total CD4+ and CD8+ T-cells responses, but does not alter T-cells activation among HCV mono-infected, and HCV/HIV-1 co-infected patients.

Clinics and Research in Hepatology and Gastroenterology(2018)

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摘要
Total T-cells immune response enhances after therapy, however, the state of immune activation may remain elevated for a longtime after the end of treatment and contribute to post-Sustained Virologic Response (SVR) consequences.
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关键词
Hepatitis C virus,Human immunodeficiency virus-1,Direct-acting antiviral,T-cell,Immune activation,Intracellular cytokine assay
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