Comprehensive assessment of myositis-specific autoantibodies in polymyositis/dermatomyositis-associated interstitial lung disease.

Hironao Hozumi,Tomoyuki Fujisawa,Ran Nakashima,Takeshi Johkoh,Hiromitsu Sumikawa,Akihiro Murakami,Noriyuki Enomoto,Naoki Inui,Yutaro Nakamura,Yuji Hosono,Yoshitaka Imura,Tsuneyo Mimori,Takafumi Suda

Respiratory Medicine（2016）

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摘要

•Serum MSAs were comprehensively measured using IP assay in PM/DM-ILD patients.•Anti-ARS and anti-MDA5 antibodies were the two major MSAs in PM/DM-ILD.•Clinical and radiographical features were different among the MSA subgroups.•Assessment of MSAs may be useful for predicting the clinical course and prognosis.

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关键词

Polymyositis,Dermatomyositis,Myositis-specific autoantibody,Interstitial pneumonia,ARS,MDA5

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