CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension.

Ricardo Celestino,Torfinn Nome,Ana Pestana,Andreas M Hoff,A Pedro Gonçalves,Luísa Pereira,Bruno Cavadas,Catarina Eloy,Trine Bjøro,Manuel Sobrinho-Simões,Rolf I Skotheim,Paula Soares

BMC cancer（2018）

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摘要

We conclude that the underexpression of CRABP1 and the overexpression of LCN2 may be useful diagnostic biomarkers in thyroid tumours with questionable malignity, and the overexpression of LCN2 and C1QL1 may be useful for prognostic purposes.

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关键词

CRABP1,CILP,C1QL1,LCN2,Cancer,Thyroid,Biomarker,TCGA,RNA sequencing,Gene expression

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