A Facile One-Pot Synthesis of Acrylated Hyaluronic Acid

A. Sigen,Qian Xu,Peter McMichael,Yongsheng Gao,Xiaolin Li,Xi Wang,Udo Greiser,Dezhong Zhou,Wenxin Wang

Chemical communications（2018）

引用 17|浏览17

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摘要

The synthesis of acrylated hyaluronic acid (HA-A) normally requires 2 to 3 steps of modification, needs laborious purification and also increases the risks of HA degradation. Here, we report that the conjugation of acrylate groups to hyaluronic acid can be successfully achieved via a new facile one-pot approach. Two types of new HA-A hydrogels (via chemical or UV crosslinking) were developed and applied for 3D cell encapsulation.

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