Composite hydrogel modified by IGF-1C domain improves stem cell therapy for limb ischemia

ACS applied materials & interfaces, Volume 10, Issue 5, 2018, Pages 4481-4493.

Cited by: 1|Views10


Stem cell treatment for critical limb ischemia yields a limited therapeutic effect due to cell loss and dysfunction caused by local ischemic environment. Biomimetic scaffolds emerge as ideal cell delivery vehicles for regulating cell fate via mimicking the components of stem cell niche. Herein, we prepared a bioactive hydrogel by mixing c...More



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